P28S04: Refractory high blood pressure

 

Bottom line: Information on high blood pressure was used to justify the management of a patient (increase dose of an anti-hypertensive medication). It contributed to avoid inappropriate procedures, and to prevent health deterioration.

 

Level 1 outcome (situational relevance): On December 9, 2008, P28 did a search at work, and during an encounter with a patient. The patient was present while P28 was doing the search, and P28 showed her an information hit. P28 retrieved two information hits about an angiotensin-converting enzyme (ACE) inhibitor, candesartan cilexetil (Atacand). The reported search objectives were: to address a clinical question, and to exchange information with another health professional. She [the patient, a woman in her seventies] had come in for a routine check-up. On the check-up I had noticed that she had been high with regards to her blood pressure for the last 1 or 2 visits. So I looked at what medications she was on and she was on Atacand, so I decided that I would increase the dose of the ACE inhibitor, before introducing a new agent to try and control her hypertension. My clinical question was how much to increase her dose by, and also the side effects that she could experience. […] Usually, […] I see the patient and then I go present my patient to a physician [supervisor] who’s watching me on a camera. So I used this information also to speak with that physician regarding why I chose to increase the Atacand versus add another agent.” According to P28, e-Therapeutics+ was in agreement with and more relevant than the information from another health professional (supervisor) and from another electronic resource (Up-to-Date). The physician didn’t remember the exact dosing recommendations for Atacand for hypertension, and what increment to increase by. […] With respect to the dosages, Up-To-Date I find, doesn’t give a lot of dosage specific recommendations.”

 

Level 2 outcome (cognitive impact): The second hit was associated with a report of positive cognitive impact (see table). Regarding practice improvement and learning, P28 stated: I learned what increment Atacand should be increased by. […] I know the denominations that Atacand comes in now, and so I wouldn’t necessarily have to look that up the next time that I want to increase someone [who is on Atacand].”

Retrieved information hits:

1) e-Therapeutics+ (CIRT): eCPS Tab – Keyword: AtacandSide effects – Table 5 (P28S04H01)

2) e-Therapeutics+ (CIRT): eCPSTab – Keyword: AtacandDosage in hypertension (P28S04H02

 

Level 3 outcome (information use): Information on Atacand was retrieved, and used to maintain (be more certain about) the medication, and to justify the management of the patient (information used as presented in e-Therapeutics+).I ended up increasing the dose of Atacand. […] We actually [gave] her 16 mg and an 8 mg, because she was so old. I didn’t want to increase her from 16 to 32 all the way.”

 

Level 4 outcome (patient health): Regarding patient health, P28 reported that the information contributed to avoid inappropriate procedures, and to prevent health deterioration. [The plan] was just avoiding to use another pill, or try to increase this pill first, before actually going onto another medication. […] So obviously, [I was hoping to help her] control the risks of stroke, heart disease, etc, to […] improve her health in the long run. [Did you have a follow-up?] Yeah yeah, I, I saw her, and her blood pressure was more improved.

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Exchange information

Practice improved

Learned something

Reminded something

Confirmed

Reassured

Justify choice

Be more certain

Prevent

Avoid

 

 

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