P18S01: Gout (secondary prevention)

 

Bottom line: Information on gout, specifically allopurinol for secondary prevention of gout, was used to maintain the management plan for a patient (prescription of allopurinol). There were no information-related patient health outcomes.

 

Level 1 outcome (situational relevance): On August 26, 2008, P18 did a search at work, by themselves, and after an encounter with a patient. They retrieved two information hits about use of allopurinol for prophylaxis of gout. The reported search objectives were: to address a clinical question, to look up something they had forgotten, to share information with a patient, and to exchange information with other health professionals. [The patient] was a man, [...] sixty eight [years old]. [...] He was referred to me [...] and I discovered that he is taking indomethacin daily for a prophylaxis of gout instead of for acute attacks so I needed to change it. So I wanted to go and look to find all the information to present to the doctor so I can get him to change the medication to allopurinol. [...] I was looking for information on dose and side effects. [...] I couldn’t remember the dosing of allopurinol for propylaxis. [...] I had to tell the patient that I was going to check [...], that I would call back to his pharmacists or to him and to let him know what we were going to do. [...] So, I sent an email to a doctor and got him to find any prescription for me, so I could change the medication. According to P18, the information from e-Therapeutics+ was in agreement with and equally relevant as the information from another electronic resource (Up-to-Date). “In terms of drug info it was similar. [...] Probably equally relevant, but less easy to use [compared to e-Therapeutics+].

 

Level 2 outcome (cognitive impact): One hit was associated with a report of positive cognitive impact (see table). Regarding learning, motivation, confirmation, reassurance and reminder, P18 stated: “[I learned from] the green highlight about Probenecid and sulfinpyrazone being a substitute, but it wasn’t really applicable for my patient (concerning P18S01H01). [...] I had thought that I was going to use allopurinol, and I just confirmed that it was a good choice for this patient and that it didn’t have any contraindications. […] I already knew the dosing and that it had to be [adapted] for kidney chronic patients, but I just can’t remember the dosing adjustments (concerning P18S01H02).

Retrieved information hits:

1) e-Therapeutics+ (CIRT): Therapeutics Tab – Keyword: Allopurinol – hyperuricemia Highlight (P18S01H01)

2) e-Therapeutics+ (CIRT): Therapeutics Tab – Keyword: Allopurinol – hyperuricemia – Dosing and side effects of allopurinol in Table 4 (P18S01H02)

 

Level 3 outcome (information use): Information on allopurinol for prophylaxis of gout was retrieved, and used to better understand a specific issue with respect to the management of the patient, and to maintain (be more certain about) the management plan for the patient (information used as presented in e-Therapeutics+). I wanted to change from indomethacin to allopurinol. [...] I needed to able to get the doctor to make a change so I wanted to have the data to be able to justify why I wanted to change. […] He [the doctor] didn’t really tell me anything. He just agreed with me.

 

Level 4 outcome (patient health): Without these information hits, P18’s management of the patient would have been the same. There was no clear relationship between the information use and patient health outcomes.

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Look up something forgotten

Share information

Exchange information

Learned something

Reminded something

Motivated to learn

Confirmed

Reassured

Be more certain

Understand issue

No outcome

 

 

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