P16S01: Malaria prevention

 

Bottom line: Information on treatment to prevent malaria was used to justify the management of a patient (combine anticoagulant and antimalarial medications, and increase the frequency of the monitoring of anticoagulation). It contributed to increase patient knowledge, and to prevent health deterioration.

 

Level 1 outcome (situational relevance): On January 8, 2009, P16 did a search at work, by themselves, and before an encounter with a patient. They retrieved three information hits about Malarone. The reported search objectives were: to address a clinical question, to share information with a patient or caregiver, to exchange information with other health professionals, and to plan, manage, coordinate, tasks with other health professionals. “The physician called and he had a patient [a man between fifty and sixty years old] going to Africa [and] who needed to take an antimalarial. […] Malarone had been recommended to him [the patient], and he wanted to know what he should do about his Warfarin treatment while he was away in Africa. […][The clinical question was] from the physician about the management of the patient’s Warfarin. […][I needed to] find out if there would be an interaction [with] the patient’s Warfarin therapy […] and then advised the physician and the patient on what to do. […][I wanted] to kind of coordinate his prescribing therapy before he left, [because] […] he is going to work as a volunteer in a hospital in Africa, so he might have to have some monitoring done while he is there.” According to P16, the information from e-Therapeutics+ was in agreement with and equally relevant as the information from another professional (pharmacist). “I talked to another pharmacist to see whether or not they had had any experience with this drug.”

 

Level 2 outcome (cognitive impact): The three hits were associated with a report of positive cognitive impact (see table). Regarding practice improvement and learning, P16 stated: “I learned what the constituents of Malarone are and how they work. […] [Now] I have an understanding of how it’s dosed. I didn’t know much about this product beforehand. […] I’ll know that this is an option for the malarial prophylaxis […] [and] I’ll have additional information going forward to deal with a similar situation.”

Retrieved information hits:

1) e-Therapeutics+ (CIRT): e-CPS Tab – Keyword: Malarone –First paragraph (Constituents) (P16S01H01)

2) e-Therapeutics+ (CIRT): e-CPS Tab – Keyword: Malarone –Dosage section (P16S01H02)

3) e-Therapeutics+ (CIRT): Drug interactions Tab – Keywords: Warfarin and Malarone – Analyse – Warfarin Reaction – Print whole page (P16S01H03)

 

Level 3 outcome (information use): Information on Malarone was retrieved, and used to better understand a specific issue with respect to the  management of the patient, and to justify the management of the patient (information used as presented in e-Therapeutics+). “We are going to give him the drug [Malarone] but, because there is a potential interaction [with Warfarin], we would monitor [the INR – International Normalized Ratio] more frequently.”

 

Level 4 outcome (patient health): Regarding patient health, P16 reported that the information contributed to increase patient knowledge, and to prevent health deterioration. “He [the patient] was [now] aware that there was a potential interaction [between Malarone and Warfarin]. […] so this way he [the doctor] could give him the right drug but just monitoring appropriately. […] Because he [the patient] would be monitored while he was away, we would hopefully prevent a situation of bleeding. [The patient knew] […] that he could correspond with me by email while he was gone.”

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Share information

Exchange information

Manage patient care

Practice improved

Learned something

Motivated to learn

Confirmed

Reassured

Justify choice

Understand issue

Prevent

Patient knowledge

 

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