P15S07: High blood pressure

 

Bottom line: Information on adverse reactions of a treatment for high blood pressure was used to maintain the management of a patient (continue medication). It contributed to increase patient knowledge about this medication (adverse reactions).

 

Level 1 outcome (situational relevance): On December 15, 2008, P15 did a search at work, by themselves, during the encounter with the patient (in the presence of the patient). They retrieved one information hit about Rasilez & hot flashes. The reported search objectives were: to address a clinical question and to share information with the patient. “She [the patient, a woman in her seventies] had resistant hypertension so we have her on Rasilez that is not covered on the Ontario Drug Benefit. […]We give her samples for a few months and now [it’s] [the Rasilez medication] about fully covered. I was trying to get her a prescription and then she would say: “oh I had these warm feeling when I wake up”. She [the patient] thinks it’s from the drug because she has had many adverse reactions to many drugs so I just looked it up. [The clinical question was] Does rasilez cause hot flashes?” According to P15, at the time of the interview, e-Therapeutics+ was the only source for information.

 

Level 2 outcome (cognitive impact): Three hits were associated with a report of positive cognitive impact (see table). Regarding reminder, P15 stated: “I already knew all these side effects [table 1 & 2]. […][Under adverse reactions] there are even more side effects, and I already knew these.” The first hit was also associated with a report of negative cognitive impact (dissatisfaction). “[…] [But] it’s pretty general. Some of it is specific some is not. If you look under digestive it is just listed, but it doesn’t say what the incidence is.”

Retrieved information hits:

1) e-Therapeutics+ (CIRT): e-CPS Tab – Keyword: Rasilez – Monograph – Adverse reactions (P15S07H01)

2) e-Therapeutics+ (CIRT): e-CPS Tab – Keyword: Rasilez – Monograph – Table 1 (P15S07H01)

3) e-Therapeutics+ (CIRT): e-CPS Tab – Keyword: Rasilez – Monograph – Table 2 (P15S07H01)

 

Level 3 outcome (information use): Information on Rasilez & hot flashes was retrieved, and used to better understand a specific issue with respect to the management of the patient, and to maintain (be more certain about) the management of a patient (information used as presented in e-Therapeutics+). “I was trying to rule out whether or not the adverse reactions were due to this drug [Rasilez] or something else. […] I just worried that there is no adverse reactions for Rasilez and then I asked her after if she could tolerate it. And she was “oh, yeah I can tolerate it”. […][So] she was going to continue [the Rasilez medication]. [… ] She has a history of stopping her medication without telling us, so I was trying to get her to still go ahead with it, keep taking her medication.”

 

Level 4 outcome (patient health): Regarding patient health, P15 reported that the information contributed to increase patient knowledge. “She [the patient] had a question to ask about whether or not this drug would cause adverse reactions, so I was able to reply that information for her.”

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Share information

Reminded something

Be more certain

Understand issue

Patient knowledge

 

 

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