P14S07: Attention-deficit hyperactivity disorder (ADHD) : Drug options

 

Bottom line: Information on Attention-deficit hyperactivity disorder (ADHD) was used to justify the management of a patient (avoid second line treatment). It contributed to avoid inappropriate treatment.

 

Level 1 outcome (situational relevance): On September 17, 2008, P14 did a search at work, by themselves, and before an encounter with a patient. They retrieved three information hits about ADHD. The reported search objectives were: to address a clinical question, to share information with a patient or caregiver, and to exchange information with other health professional. “The patient’s parents had brought in an article on this [new] drug wondering about it for their child instead of stimulant medications […]The patient [a teenager girl] [and her] mom came in and they were asking about treatment choices [for ADHD] and they were specifically asking about Strattera which is Atomoxetine. […] I needed more information about the management of ADHD than the Pharmacist letter was giving me. […] It [the Pharmacist letter] was just kind of drug information and [it] talked about some of the recent controversies around Strattera. […] I had to talk to the parents and the daughter about medication choices, […] [and] I had to share the information about the dosing of Concerta [the first line treatment] with the physician.” According to P14, the information from e-Therapeutics+ was in agreement with and less relevant compared to the information from another textbook or journal (Pharmacist letter). “The Pharmacist letter does a good job of detailing the drug itself. […] And then I went to Therapeutic Choices to read up on the management […].”

 

Level 2 outcome (cognitive impact): Three hits were associated with a report of positive cognitive impact (see table). Regarding learning, P14 stated: “I learned something new from that whole Atomoxetine paragraph [in the Pharmacologic choices section]. [And][…] I didn’t really know the place in therapy of this new agent for ADHD, Strattera, […] it puts it not first line.” Regarding reminder, P14 stated: “I’m reminded of something I already knew [with] the pharmacologic choices on psychostimulants (first hit) […][and] the dosing of methylphenidate (third hit).”

Retrieved information hits:

1) e-Therapeutics+ (CIRT): Therapeutics Tab – Keyword: ADHD – Pharmacologic choices (P14S07H01 = L + RM)

2) e-Therapeutics+ (CIRT): Therapeutics Tab – Keyword: ADHD – Highlight (P14S07H02 = L)

3) e-Therapeutics+ (CIRT): Therapeutics Tab – Keyword: ADHD – Table 2: Drugs used in ADHD (P14S07H03 = RM + D)

 

Level 3 outcome (information use): Information on ADHD was retrieved, and used to justify the management of a patient (information used as presented in e-Therapeutics+). “I used this information to justify that it [Strattera] wasn’t the first line drug.”

 

Level 4 outcome (patient health): Regarding patient health, P14 reported that the information contributed to avoid inappropriate treatment. “[In the second] encounter was the physician, myself, the mom, the dad and the daughter. There were five of us. [...] I said to them [the parents of the patient] that there is a place for Atomoxetine in the treatment of ADHD, but it’s a relatively new drug and that means it’s not first line, especially when you treat children. We don’t know everything there is to know about that drug yet so we probably should stick with what we know for sure. [We avoided] going with the second line agent [Atomoxetine - Strattera] […].”

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Share information

Exchange information

Learned something

Reminded something

Justify choice

Avoid

 

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