P04S07: Hypercholesterolemia

 

Bottom line: Information on hypercholesterolemia was used to justify the management of a patient (change medication to lower cholesterol). There were no information-related patient health outcomes.

 

Level 1 outcome (situational relevance): On October 17, 2008, P04 did a search at work, by themselves, and before an encounter with a patient. They retrieved one information hit about dyslipidemia. The reported search objectives were: to address a clinical question and to look up something they forgot. “[The patient was a man] in his [late] thirties […] who has type II diabetes [and hypercholesterolemia]. He is of Philippino descent. And he was started on a statin recently. And he was having elevated CPK [Creatine Phosphokinase] values. So, I had to take him off of his statin. And I was trying to figure out what the best second line option would be for this man. […] I just wanted to rub my head around […] This is all reviewed it. We usually start with statins [for hypercholesterolemia]. It’s not often that we have to switch them up. So, it’s information that I have come across in the past. I just wanted to review it.” According to P04, e-Therapeutics+ was the only source for information, and the found information was relevant.

 

Level 2 outcome (cognitive impact): One hit was associated with a report of positive cognitive impact (see table). Regarding confirmation, reassurance, and reminder, P04 stated: “I’ve taken him off the medication [side effect confirmed by the retrieved information] I don’t have anything other than that. […] [I am reassured] that I’m on the right track for what to do next.

Retrieved information hit(s):

1) e-Therapeutics+ (CIRT): Therapeutics tab – dyslipidemia – pharmacologic choices section – lipid lowering agents (P04S07H01).

 

Level 3 outcome (information use): Information on dyslipidemia was retrieved, and used to justify the management of the patient (information used as presented in e-Therapeutics+). “We discussed his options. His CPK levels still haven’t come down to baseline. So we just discussed the options that we were going to wait until he went back to baseline and then we would look at putting him on another agent. […] We were going to wait a couple of weeks and he was going to recheck his blood [CPK] and we left it at that. And once he normalizes we’ll start him on a new medication, most likely a cholesterol absorption inhibitor. […] The whole point would be to help make a decision on what the next medication would be. So, the information used [on different types of drugs that lower cholesterol] will be helpful in deciding what medication to put him on. […] I am confident that this is the right choice to take him off the medication and put him on something else.

 

Level 4 outcome (patient health): There was no information-related patient health outcomes (no follow-up yet). The new medication “has not been implemented yet.”

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Look up something forgotten

Reminded something

Confirmed

Reassured

Justify choice

No outcome

 

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