P03S06: Benzodiazepines (sedation for a test)

 

Bottom line: Information on benzodiazepines was used to maintain the management of the patient (sedation in preparation for a test). There were no information-related patient health outcomes.

 

Level 1 outcome (situational relevance): On December 16, 2008, P03 did a search at work, with a nurse educator, and before an encounter with a patient. They retrieved two information hits about Versed and impaired cognition. The reported search objectives were: to address a clinical question, to share the information with a patient or caregiver, to exchange information with other health professionals, and to plan, manage, coordinate, delegate or monitor tasks with other health professionals. “[The patient was a] woman [in her] early fifties. […] We were going to be sending this patient for a test, for scope, for which she needed to be sedated with Midazolam. And she wasn’t diagnosed with Alzheimer’s but she is having some cognitive changes. She likely will soon be diagnosed so I just wanted to make sure that there was no contraindication for her having the sedation, or if it was going to extend the life of the drug or anything like that. […] I wanted to be able to tell the patient that it was safe to have the sedation or to warn them that the side effects may be prolonged or whatever the case may be. So I just wanted to have a better understanding to share with the patient. […] The nurse educator was also working with this patient and had other patients that are similar, so I wanted to make sure that she was aware of the plan.” According to P03, the information from e-Therapeutics+ was more relevant than the information from another paper-based resource (The Merck Manual of Geriatrics). “[I found] nothing specifically to talk about Midazolam [in the other resource].

 

Level 2 outcome (cognitive impact): Two hits were associated with a report of positive cognitive impact (see table). Regarding practice improvement, P03 stated: “I gained knowledge in this area where I wasn’t confident in my knowledge. […] I would know how to better prepare patients for tests that have some risk of cognitive impairment, if they can be using these drugs. […] I was not sure [and I learned something] (regarding P03S06H01).

Retrieved information hit(s):

1) e-Therapeutics+ (CIRT): e-CPS tab – Versed – Midazolam HCL - Benzodiazepines (CPhA monograph) – Contraindications, warnings and precaution (P03S06H01).

2) e-Therapeutics+ (CIRT): e-CPS tab – Versed – Midazolam HCL – Benzodiazepines (CPhA monograph) – Table 3: Benzodiazepines – drug interactions (P03S06H02).

 

Level 3 outcome (information use): Information on Versed and Alzheimer’s was retrieved, and used to maintain (be more certain about) the management of the patient (information used as presented in e-Therapeutics+). “I later met with the patient and proceeded to tell them about the test they were going to have [endoscopy] and the information related to the drug that they would get for the test. […] The plan was for the patient to go ahead with the test. I was checking to make sure that it was safe to do so (regarding both hits).”

 

Level 4 outcome (patient health): Without this information, P03’s management of the patient would have been the same. There were no clear relationships between the use of information and expected patient health outcomes.

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Share information

Exchange information

Manage patient care

Practice improved

Learned something

Motivated to learn

Be more certain

No outcome

 

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