P01S04: Sexual dysfunction

 

Bottom line: Information on sexual dysfunction induced by Selective Serotonin Reuptake Inhibitor (SSRI) was used to justify the management of the patient, and persuade the patient to make a change (replace medication). There were no information-related patient health outcomes.

 

Level 1 outcome (situational relevance): On June 13, 2008, P01 did a search at work, with a nurse practitioner student, and during an encounter with a patient. They retrieved one information hit about sexual dysfunction induced by Selective Serotonin Reuptake Inhibitor (SSRI). The reported search objectives were: to address a clinical question, to share the information with a patient, and to exchange information with other health professionals. “It was a man and he had depression and he was on an antidepressant, and I think he had been on a couple of them, I'm not completely sure, but they all caused him sexual dysfunction. He couldn't get an erection, so we were trying to find something for his depression that would not result in impotence. [...] I was just trying to figure out which drug was more appropriate for people who had sexual dysfunction from most antidepressants.[…] So I could ask the patient ‘do you want to try this?’ And, I could share that with him and he could say yes and no. […] I had the nurse [practitioner student] with me, and that way, if I give her the information, it's something that she can learn from it. […] I basically looked at the adverse effects column […] for almost all of them it says sexual dysfunction […] except for the one that I chose [Wellbutrin].” According to P01, e-Therapeutics+ was the only source for information, and the found information was relevant.

 

Level 2 outcome (cognitive impact): One hit was associated with a report of positive cognitive impact (see table). Regarding practice improvement, P01 stated: “Now that I know that there are alternatives I can make suggestions for patients so that they don't have to suffer with sexual dysfunction when they're on an antidepressant and I know now what I can switch them to, if they want to try something different.”

Retrieved information hit(s):

1) e-Therapeutics+ (CIRT): Therapeutic tab – depression - table 2 – extract on sexual dysfunction (P01S04H01).

 

Level 3 outcome (information use): Information on SSRI-induced sexual dysfunction was retrieved for a patient, and used to justify the management of the patient and to persuade the patient and other health professionals to make a change (information used as presented in e-Therapeutics+). “We gave him Wellbutrin […]. I just started them [the patient] on the initial dose that was listed there, and then I advised them to come back so that we could pump it up a little bit to the regular maintenance dose. […] He was on another antidepressant. I think it was either Celexa or Cipralex or something like that. So we modified his treatment. […] I had to persuade him by saying “I know, you should go back and see Dr. Blank [pseudonym]. I know, I'm not your regular provider but do you want to try this [Wellbutrin], see how it goes, and then you can come back and see me or see Dr. Blank and we can see how things are going?” [...] I guess that there's always a chance that the doctor might just say “no no no, let's not try that one, keep going with Cipralex and it's the better one for you.” […] And sometimes patients are very adamant that they don’t want any suggestions from other providers except their own doctor.”

 

Level 4 outcome (patient health): The information-related patient health outcomes were unknown (no follow-up). “He did not come back, so I do not know how well it worked.”

 

 

Levels of outcome of information-seeking

 

Situational relevance

Positive cognitive impact

Information use

Patient health

Address a clinical question

Share information

Exchange information

Practice improved

Learned something

Motivated to learn

Reassured

Persuade

Justify choice

No outcome

 

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